Recently identified as a polar granule component, PIWI proteins appear to control germ cell formation so much so that in the absence of PIWI proteins there is a significant decrease in germ cell formation.

PIWI proteins play crucial roles during germline development and gametogenesis of many metazoan species, from germline determination and germline stem cell maintenance to meiosis, …

Sep 14, 2022 · PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells, …

Apr 29, 2025 · PIWI-interacting RNAs (piRNAs) are a distinct class of small non-coding RNAs, typically ranging from 24 to 31 nucleotides in length. This size range sets them apart from microRNAs …

Jul 15, 2025 · PiWi is a much-needed abbreviation for the German term Pilzwiderstandsfähige Rebsorten, which translates to fungus-resistant grape variety.

Nov 29, 2023 · Piwi-interacting RNAs (piRNAs) are emerging small non-coding RNAs that are 24–31 nucleotides in length. Previous studies on piRNAs were mainly limited to evaluating the binding to …

The founding member of the PIWI subclade is the Drosophila Piwi, which was originally discovered owing to its function in germline stem cell (GSC) self-renewal and germline development.

PIWI proteins and piRNAs are mostly known for their role in transposon silencing during animal germ cell development. piRNAs are small non-coding RNAs that require PIWI proteins for their biogenesis …

Inspired by a recent workshop on PIWI proteins and piRNAs, this commentary aims to summarize fundamental aspects of piRNA biology, highlight recent advances, and discuss key outstanding …

Dec 9, 2024 · In the current review, we explore the multifaceted roles of piRNAs and PIWI proteins in numerous biological contexts, emphasizing their involvement in stem cell maintenance, …